Sibylle J Hauske Selected Research

aminoacyl-histidine dipeptidase

1/2020	Human carnosinase 1 overexpression aggravates diabetes and renal impairment in BTBROb/Ob mice.
4/2019	Carnosinase concentration, activity, and CNDP1 genotype in patients with type 2 diabetes with and without nephropathy.
1/2019	Identification and characterisation of carnostatine (SAN9812), a potent and selective carnosinase (CN1) inhibitor with in vivo activity.
1/2019	Detection of carnosinase-1 in urine of healthy individuals and patients with type 2 diabetes: correlation with albuminuria and renal function.

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Sibylle J Hauske Research Topics

Disease

8	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2016
7	Diabetic Nephropathies (Diabetic Nephropathy) 12/2020 - 01/2017
5	Albuminuria 12/2020 - 10/2017
4	Kidney Diseases (Kidney Disease) 12/2020 - 01/2018
3	Chronic Renal Insufficiency 01/2022 - 12/2018
2	Proteinuria 01/2020 - 01/2020
2	Glycosuria 01/2020 - 01/2019
2	Heart Failure 01/2020 - 12/2018
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	Edema (Dropsy) 01/2022
1	Hyperkalemia 01/2022
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2020
1	Inflammation (Inflammations) 01/2019
1	Body Weight (Weight, Body) 12/2018
1	Hypertrophy 10/2017
1	Disease Progression 01/2016
1	Hyperglycemia 01/2016

Drug/Important Bio-Agent (IBA)

4	AlbuminsIBA 12/2020 - 01/2018
4	CreatinineIBA 12/2020 - 01/2018
4	aminoacyl-histidine dipeptidaseIBA 01/2020 - 01/2019
3	Glucose (Dextrose)FDA LinkGeneric 08/2020 - 10/2017
3	CarnosineIBA 01/2019 - 01/2016
2	empagliflozinIBA 01/2022 - 12/2020
2	SodiumIBA 08/2020 - 12/2018
1	AldosteroneIBA 01/2020
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2020
1	AngiotensinsIBA 01/2020
1	NF-kappa B (NF-kB)IBA 01/2019
1	1-(2-chloroethyl)-1-nitrosourea (CNU)IBA 01/2019
1	LDL CholesterolIBA 12/2018
1	Sodium-Glucose Transporter 2 InhibitorsIBA 12/2018
1	EnzymesIBA 10/2017
1	IronIBA 01/2016
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016

Therapy/Procedure

1	Surgical Amputation (Amputations) 01/2022
1	Renal Dialysis (Hemodialysis) 01/2017